UK plans COVID-19 “challenge” preliminaries that purposely contaminate volunteers

UK plans COVID-19 “challenge” preliminaries that purposely contaminate volunteers



England will assist with financing preliminaries utilizing a produced COVID-19 infection to purposely taint youthful sound volunteers; with the expectation of quickening the improvement of antibodies against it.


The government said on Tuesday it will invest 33.6 million pounds ($43.5 million) in the so-called “human challenge”; trials in partnership with Imperial College London, laboratory and trial services company hVIVO and the Royal Free London NHS Foundation Trust.


If approved by regulators and an ethics committee, the studies will start in January with results expected by May 2021, the government said.


Using controlled doses of virus, the aim of the research team  will initially be to discover the smallest amount of virus; it takes to cause COVID-19 infection in small groups of healthy young people, aged between 18 and 30; who are  at the lowest risk of harm, the scientists leading the studies said in a briefing.


Up to 90 volunteers could be involved at the initial stages; they said, and virus to be used will be manufactured in labs at London’s Great Ormond Street Hospital.


Chris Chiu, an Imperial College scientist on the team, said the experiments would rapidly increase understanding of COVID-19; and the SARS-CoV2 virus that causes it, as well as accelerating development of potential new treatments and vaccines.

He said that while studies have show remdesivir has little or no effect on severe COVID-19 cases; his team has a “strong belief” that it will be an effective treatment if given in the very earliest stages of infection.


A spokeswoman for the World Health Organization said that there are; “very important ethical considerations” when approaching such human challenge trials.

What is basic is that if individuals are thinking about this, it must be directed by a morals panel and the volunteers must have full assent. What’s more, they should choose the volunteers so as to limit their danger,” she told correspondents in Geneva.


Chiu said his group’s “number one need is the wellbeing of the volunteers”.


“No investigation is totally hazard free; however (we) will be endeavoring to guarantee we make the dangers as low as we can,” he said.


England’s hVIVO, a unit of drug administrations organization Open Orphan ORPH.L; said a week ago it was doing primer work for the preliminaries.






Source: Reuters

About The Author

Osigweh Lilian Oluchi is a graduate of the University of Lagos where she obtained a B.A (Hons) in English, Masters in Public and International affairs (MPIA). Currently works with 1stnews as a Database Manager / Writer. [email protected]

Related posts

Leave a Reply

Your email address will not be published. Required fields are marked *